Most of the reactions in the past have involved simply substitutions or combining different compounds.
Miniscale versions of both Background on reaction in loose-leaf pages. Since this is a preparation, or synthesis, lab you must have a reaction equation with structures in your notebook. You need appropriate physical and hazard data for all of the substances used and prepared in the lab.
You must include a diagram of the apparatus, including the hot water bath and its support and the location of the utility clamp. It is imperative that the Grignard reagent does not come in contact with water during its preparation or use, until you add the ammonium chloride solution.
To help with this the stockroom will put an assortment of glassware, including the setup flask, condenser, addition funnel, two glass stopcockstwo beakers, a mL graduated cylinder, and stirring rod in the oven before the lab.
All of the ether used during the preparation of the phenylmagnesium bromide and its reaction with acetophenone must be anhydrous. Do not allow any glassware that has not been dried in the oven to come in contact with your reaction mixture or a reagent used except for unused Pasteur pipets or pipets supplied with reagents.
Procedure - use this instead of the one in the loose-leaf pages Setup: Assemble the apparatus, complete with stoppers and the stopcock in the funnel as quickly as possible to avoid introducing moisture. You will find the drying tubes in a dessicator at the front of the room and the teflon stopcocks in a tray or plate on the front desk.
Note that the diagram includes glassware only, not clamps, baths, tubing, etc. Clamp the center neck of the flask securely, and obviously run water through the condenser. The dish needs to be on a lab jack or other platform. Then get the reagents.
Weigh after sanding and then put the Mg in the flask. Immediately close the flask. Add one iodine crystal through the middle neck and immediately re-stopper the flask.
Replace the stopper on the addition funnel. Add approximately half of the solution from the addition funnel to the mixture in the flask. Open the center neck and use your DRY stirring rod to crush some of the Mg. If you don't feel comfortable doing this, ask the instructor for help.
This step is probably not necessary if you used Mg ribbon. You are looking for the following as evidence of reaction: The reaction should seem to go on its own even when you remove the water bath for a few minutes. Do not let the reaction stop bubbling--if it seems to stop, reapply the bath.
Have your instructor check your reaction to make sure it is well underway before proceeding. Ask if you should keep the water bath under the reaction mixture. Then add the rest of the bromobenzene-ether mixture from the addition funnel at a rate so that the reaction continues to reflux or drops per second if you are heating it.A lab report about Preparation and usage of a Grignard reagent in order to synthesize Benzoic acid from Solid CO2 (Dry Ice) and a Bromo-Benzene Grignard.
Grignard Synthesis of Triphenylmethanol From Benzophenone. Enviado por.
d-fbuser Aldol Condensation. Enviado por. Fajriah Fajriah. Grignard Reaction. Enviado por. jayhov. caninariojana.com://caninariojana.com Grignard Reaction with a Ketone: Triphenylmethanol.
Introduction: The purpose of this lab is to prepare phenylmagnesium bromide, a Grignard reagent, and react it with benzophenone to give triphenylmethanol. Grignard reagents are very reactive and must be synthesized in an environment free of water or any other source of potential proton caninariojana.com://caninariojana.com The synthesis of a Grignard reagent was required for the Grignard reaction of this experiment to occur, therefore, phenylmagnesium bromide was produced before further proceeding with the preparation of caninariojana.com://caninariojana.com Synthesis of Aspirin Lab Report; Synthesis of Aspirin Lab Report.
Words Mar 3rd, 12 Pages. The Grignard Synthesis of Triphenylmethanol Organic Chemistry Lab II March 19, Abstract The purpose of this experiment was to synthesize the Grignard reagent, phenyl magnesium bromide, and then use the manufactured Grignard reagent to. The Grignard Synthesis of Triphenylmethanol Organic Chemistry Lab II March 19, Abstract The purpose of this experiment was to synthesize the Grignard reagent, phenyl magnesium bromide, and then use the manufactured Grignard reagent to synthesize the alcohol, triphenylmethanol, by reacting with benzophenone and protonation by H3O+.
Lab Report: Write a “standard synthesis-style” lab report.
A summary of what a standard synthesis- style lab report should look like is described in more detail two pages after this. This must include calculations, observations, results, and analysis, in addition to answers to the assigned postlab caninariojana.com